تعویض کامل مفصل زانو در بیماران مبتلا به ناهنجاری‌های خارج‌مفصلی )چالش‌ها، روش‌ها و نتایج(

نوع مقاله : مروری

نویسندگان

مرکز تحقیقات استخوان، مفصل و بافت های مرتبط بیمارستان اختر، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

10.22034/ijos.2026.243324
چکیده
چکیده
اجرای جراحی تعویض کامل مفصل زانو (TKA) در بیمارانی که با ناهنجاری‌های خارج‌مفصلی مواجه هستند، با چالش‌های جراحی پیچیده و قابل‌توجهی همراه است که می‌تواند تأثیرات مستقیم و غیرمستقیمی بر نتایج درمانی داشته باشد. این ناهنجاری‌ها اغلب مستلزم برنامه‌ریزی دقیق‌تر و اتخاذ راهبردهای جراحی متناسب با شرایط هر بیمار هستند تا هم‌راستایی بیومکانیکی اندام حفظ شده و عملکرد مطلوب مفصل تضمین شود. از جمله این راهبردها می‌توان به اصلاحات داخل‌مفصلی و استئوتومی‌های خارج‌مفصلی اشاره کرد که انتخاب هر یک بر اساس ویژگی‌های بالینی بیمار، محل و شدت ناهنجاری صورت می‌گیرد. در این راستا، فناوری‌های نوین نظیر جراحی با کمک رایانه و سیستم‌های روباتیک به‌عنوان ابزارهای پیشرفته مطرح شده‌اند که با افزایش دقت در برنامه‌ریزی و اجرای عمل، احتمال بروز خطاهای جراحی را کاهش داده و به بهبود پیامدهای بالینی کمک می‌کنند. این مقاله با هدف ارائه مروری جامع بر رویکردهای درمانی و الگوریتم‌های تصمیم‌گیری در مدیریت TKA در بیماران مبتلا به ناهنجاری‌های خارج‌مفصلی تدوین شده است و در عین حال بر اهمیت ارزیابی دقیق پیش‌ازعمل، تصویربرداری پیشرفته و برنامه‌ریزی چندرشته‌ای تأکید دارد. همچنین، راهکارهای عملی برای بهینه‌سازی نتایج عملکردی، کاهش عوارض احتمالی و افزایش طول عمر پروتز ارائه می‌شود.


کلیدواژه‌ها

موضوعات

عنوان مقاله English

Total Knee Arthroplasty in Patients with Extra-articular Deformities (Challenges, Techniques, and Outcomes)

نویسندگان English

Mohammad Azizi
Hooshmand Zarei
Mahyar Mahdavi
Seyed Mohammadmisagh Moteshakereh
Miad Nosratpour
Mana Zaker Moshfegh
Hamidreza Mosleh
Morteza Kazemi
Bone Joint and Related Tissues Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده English

Abstract
Performing total knee arthroplasty (TKA) in patients with extra-articular deformities presents complex and significant surgical challenges that can have both direct and indirect impacts on treatment outcomes. These deformities often require more meticulous planning and tailored surgical strategies to maintain biomechanical alignment of the joint and ensure optimal patient function. Among these strategies are intra-articular corrections and extra-articular osteotomies, with the choice depending on the specific characteristics of the patient and the severity of the deformity. In this context, advanced technologies such as computer-assisted surgery and robotic systems have emerged as innovative tools that enhance accuracy in surgical planning and execution, minimize the risk of surgical errors, and facilitate improved clinical outcomes. This article provides a comprehensive review of current best practices and emerging trends in managing TKA for patients with extra-articular deformities, while also emphasizing the importance of multidisciplinary preoperative planning, advanced imaging assessment, and patient-specific risk evaluation. It further discusses structured decision-making algorithms to guide the selection of appropriate corrective techniques, with careful attention to soft-tissue balance, implant positioning, and long-term stability. Collectively, these considerations aim to optimize functional outcomes, reduce complications, and improve implant longevity in this challenging patient population.

کلیدواژه‌ها English

Total knee arthroplasty
Knee
Osteotomy
outcomes
1.     Franzoni S, Rossi SMP, Cassinadri A, Sangaletti R, Benazzo F. Perioperative pain management in total knee arthroplasty: a narrative review of current multimodal analgesia protocols. Appl Sci. 2023; 13(6): 3798. doi:10.3390/app13063798.
2.     González-Sáenz-de-Tejada M, Quintana JM, Arenaza JC, Azcarate-Garitano JR, Esnaola-Guisasola PM, García-Sánchez I, Baguer-Antonio A, Bilbao-González A. Long-term health related quality of life in total knee arthroplasty. BMC Musculoskelet Disord. 2023 Apr 25; 24(1): 327. doi: 10.1186/s12891-023-06399-6. PMID: 37098518; PMCID: PMC10127408.
3.     Rajgopal A, Vasdev A, Dahiya V, Tyagi VC, Gupta H. Total knee arthroplasty in extra articular deformities: A series of 36 knees. Indian J Orthop. 2013 Jan; 47(1): 35-9. doi: 10.4103/0019-5413.106893. PMID: 23532339; PMCID: PMC3601231.
4.     Meng C, Yang S, Zhang Y, Yang L, Shi H, Xu Y, Li C. Simulation of osteotomy in total knee arthroplasty with femoral extra-articular deformity assisted by artificial intelligence: a study based on three-dimensional models. J Orthop Surg Res. 2024 Oct 10; 19(1): 641. doi: 10.1186/s13018-024-05126-8. PMID: 39385180; PMCID: PMC11465894.
5.     Sculco PK, Kahlenberg CA, Fragomen AT, Rozbruch SR. Management of Extra-articular Deformity in the Setting of Total Knee Arthroplasty. J Am Acad Orthop Surg. 2019 Sep 15; 27(18): e819-e830. doi: 10.5435/JAAOS-D-18-00361. PMID: 30624304.
6.     Vedoya SP, Sel HD. Total knee arthroplasty and extra-articular deformity: Deformity correction with intra-articular bone resections. 10 years follow up. J Orthop. 2021 Jan 30; 23: 219-224. doi: 10.1016/j.jor.2021.01.007. PMID: 33642818; PMCID: PMC7887331.
7.     Paley D. Principles of deformity correction. 2nd ed. Berlin: Springer; 2014.
8.     Krettek C, Miclau T, Grün O, Schandelmaier P, Tscherne H. Intraoperative control of axes, rotation and length in femoral and tibial fractures. Technical note. Injury. 1998; 29 Suppl 3: C29-39. doi: 10.1016/s0020-1383(98)95006-9. PMID: 10341895.
9.     Kettelkamp DB, Hillberry BM, Murrish DE, Heck DA. Degenerative arthritis of the knee secondary to fracture malunion. Clin Orthop Relat Res. 1988 Sep; (234): 159-69. PMID: 3409571.
10.   Tetsworth K, Paley D. Malalignment and degenerative arthropathy. Orthop Clin North Am. 1994 Jul; 25(3): 367-77. PMID: 8028880.
11.   Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RM, Reijman M, Pols HA, Bierma-Zeinstra SM. Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheum. 2007 Apr; 56(4): 1204-11. doi: 10.1002/art.22515. PMID: 17393449.
12.   Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA. 2001 Jul 11; 286(2): 188-95. doi: 10.1001/jama.286.2.188. Erratum in: JAMA 2001 Aug 15;286(7):792. PMID: 11448282.
13.   Cerejo R, Dunlop DD, Cahue S, Channin D, Song J, Sharma L. The influence of alignment on risk of knee osteoarthritis progression according to baseline stage of disease. Arthritis Rheum. 2002 Oct; 46(10): 2632-6. doi: 10.1002/art.10530. PMID: 12384921.
14.   Felson DT, Niu J, Gross KD, Englund M, Sharma L, Cooke TD, Guermazi A, Roemer FW, Segal N, Goggins JM, Lewis CE, Eaton C, Nevitt MC. Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: findings from the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative. Arthritis Rheum. 2013 Feb; 65(2): 355-62. doi: 10.1002/art.37726. PMID: 23203672; PMCID: PMC3558618.
15.   Sharma L, Song J, Dunlop D, Felson D, Lewis CE, Segal N, Torner J, Cooke TD, Hietpas J, Lynch J, Nevitt M. Varus and valgus alignment and incident and progressive knee osteoarthritis. Ann Rheum Dis. 2010 Nov; 69(11): 1940-5. doi: 10.1136/ard.2010.129742. Epub 2010 May 28. PMID: 20511608; PMCID: PMC2994600.
16.   Tanamas S, Hanna FS, Cicuttini FM, Wluka AE, Berry P, Urquhart DM. Does knee malalignment increase the risk of development and progression of knee osteoarthritis? A systematic review. Arthritis Rheum. 2009 Apr 15; 61(4): 459-67. doi: 10.1002/art.24336. PMID: 19333985.
17.   Paley D, Herzenberg JE, Tetsworth K, McKie J, Bhave A. Deformity planning for frontal and sagittal plane corrective osteotomies. Orthop Clin North Am. 1994 Jul; 25(3): 425-65. PMID: 8028886.
18.   Mullaji A, Shetty GM. Computer-assisted total knee arthroplasty for arthritis with extra-articular deformity. J Arthroplasty. 2009 Dec; 24(8): 1164-9.e1. doi: 10.1016/j.arth.2009.05.005. Epub 2009 Jul 4. PMID: 19577897.
19.   Singer FR, Bone HG 3rd, Hosking DJ, Lyles KW, Murad MH, Reid IR, Siris ES; Endocrine Society. Paget's disease of bone: an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2014 Dec; 99(12): 4408-22. doi: 10.1210/jc.2014-2910. PMID: 25406796.
20.   Loures FB, Correia W, Reis JH, Pires E Albuquerque RS, de Paula Mozela A, de Souza EB, Maia PV, Barretto JM. Outcomes after knee arthroplasty in extra-articular deformity. Int Orthop. 2019 Sep; 43(9): 2065-2070. doi: 10.1007/s00264-018-4147-9. Epub 2018 Sep 14. PMID: 30215100.
21.   Insall J. Surgical techniques and instrumentation in total knee arthroplasty. In: Insall J, Scott WN, editors. Surgery of the knee. 3rd ed. Philadelphia: Churchill Livingstone; 2001. p. 1553–1620.
22.   Meloni MC, Hoedemaeker RW, Violante B, Mazzola C. Soft tissue balancing in total knee arthroplasty. Joints. 2014 May 8; 2(1): 37-40. PMID: 25606540; PMCID: PMC4295665.
23.   Ranawat AS, Ranawat CS, Elkus M, Rasquinha VJ, Rossi R, Babhulkar S. Total knee arthroplasty for severe valgus deformity. J Bone Joint Surg Am. 2005 Sep; 87 Suppl 1(Pt 2): 271-84. doi: 10.2106/JBJS.E.00308. PMID: 16140800.
24.   Ritter MA, Berend ME, Meding JB, Keating EM, Faris PM, Crites BM. Long-term followup of anatomic graduated components posterior cruciate-retaining total knee replacement. Clin Orthop Relat Res. 2001 Jul; (388): 51-7. doi: 10.1097/00003086-200107000-00009. PMID: 11451132.
25.   Brouwer GM, van Tol AW, Bergink AP, Belo JN, Bernsen RM, Reijman M, Pols HA, Bierma-Zeinstra SM. Association between valgus and varus alignment and the development and progression of radiographic osteoarthritis of the knee. Arthritis Rheum. 2007 Apr; 56(4): 1204-11. doi: 10.1002/art.22515. PMID: 17393449.
26.   Tanzer M, Makhdom AM. Preoperative Planning in Primary Total Knee Arthroplasty. J Am Acad Orthop Surg. 2016 Apr; 24(4): 220-30. doi: 10.5435/JAAOS-D-14-00332. PMID: 26990712.
27.   Parratte S, Van Overschelde P, Bandi M, Ozturk BY, Batailler C. An anatomo-functional implant positioning technique with robotic assistance for primary TKA allows the restoration of the native knee alignment and a natural functional ligament pattern, with a faster recovery at 6 months compared to an adjusted mechanical technique. Knee Surg Sports Traumatol Arthrosc. 2023 Apr; 31(4): 1334-1346. doi: 10.1007/s00167-022-06995-4. Epub 2022 May 13. PMID: 35552475.
28.   Sathikumar AS, Jacob G, Varghese J, Mathew V. Total Knee Arthroplasty in Paget's Disease using 3D-Printed Patient-Specific Femoral Jig - A Case Report. J Orthop Case Rep. 2023 Aug; 13(8): 84-88. doi: 10.13107/jocr.2023.v13.i08.3826. PMID: 37654769; PMCID: PMC10465753.
29.   Beckers G, Kiss MO, Massé V, Malavolta M, Vendittoli PA. Personalized total knee arthroplasty in patients with extra-articular deformities. EFORT Open Rev. 2024 Jul 1; 9(7): 646-657. doi: 10.1530/EOR-23-0215. PMID: 38949174; PMCID: PMC11297404.
30.   Catani F, Digennaro V, Ensini A, Leardini A, Giannini S. Navigation-assisted total knee arthroplasty in knees with osteoarthritis due to extra-articular deformity. Knee Surg Sports Traumatol Arthrosc. 2012 Mar; 20(3): 546-51. doi: 10.1007/s00167-011-1602-1. Epub 2011 Jul 29. PMID: 21800169.
31.   Veltman ES, van Wensen RJA, Defoort KC, van Hellemondt GG, Wymenga AB. Single-stage total knee arthroplasty and osteotomy as treatment of secondary osteoarthritis with severe coronal deviation of joint surface due to extra-articular deformity. Knee Surg Sports Traumatol Arthrosc. 2017 Sep; 25(9): 2835-2840. doi: 10.1007/s00167-015-3889-9. Epub 2015 Dec 12. PMID: 26658561.
32.   Bagaria V, Kulkarni RV, Sadigale OS, Sahu D, Parvizi J, Thienpont E. Varus Knee Deformity Classification Based on Degree and Extra- or Intra-Articular Location of Coronal Deformity and Osteoarthritis Grade. JBJS Rev. 2021 Oct 25; 9(10). doi: 10.2106/JBJS.RVW.20.00296. PMID: 34695035.
33.   Wallace SJ, Greenstein MD, Fragomen AT, Reif TJ, Rozbruch SR. Staged Extra-Articular Deformity Correction in the Setting of Total Knee Arthroplasty. Arthroplast Today. 2023 Nov 9; 24: 101247. doi: 10.1016/j.artd.2023.101247. PMID: 38023645; PMCID: PMC10663752.
34.   Tawari GJK, Maheshwari R, Madan SS. Extra-articular deformity correction using Taylor spatial frame prior to total knee arthroplasty. Strategies Trauma Limb Reconstr. 2018 Nov; 13(3): 179-184. doi: 10.1007/s11751-018-0310-5. Epub 2018 Mar 20. PMID: 29556929; PMCID: PMC6249143.
35.   Liu Z, Pan X, Zhang X. Total knee arthroplasty using navigation system for severe osteoarthritis with extra-articular deformity. Eur J Orthop Surg Traumatol. 2013 Jan; 23(1): 93-6. doi: 10.1007/s00590-011-0912-9. Epub 2011 Nov 25. PMID: 23412413.
36.   Hazratwala K, Matthews B, Wilkinson M, Barroso-Rosa S. Total knee arthroplasty in patients with extra-articular deformity. Arthroplast Today. 2016 Jan 12; 2(1): 26-36. doi: 10.1016/j.artd.2015.11.002. PMID: 28326394; PMCID: PMC4957157.
37.   Rossi R, Cottino U, Bruzzone M, Dettoni F, Bonasia DE, Rosso F. Total knee arthroplasty in the varus knee: tips and tricks. Int Orthop. 2019 Jan; 43(1): 151-158. doi: 10.1007/s00264-018-4116-3. Epub 2018 Aug 23. PMID: 30141140.
38.   Chua W, Wang W. Intra-articular correction of extra-articular tibial deformities with total knee arthroplasty. Int J Surg Case Rep. 2013;4(3):276-8. doi: 10.1016/j.ijscr.2012.12.001. Epub 2012 Dec 21. PMID: 23353706; PMCID: PMC3604651.
39.   John R, Sherman K, Sharma H. Surgical principles for complex primary total knee arthroplasty in the presence of extra-articular deformity. J Orthop. 2022 Sep 6; 34: 295-303. doi: 10.1016/j.jor.2022.08.017. PMID: 36164287; PMCID: PMC9508380.
40.   Amiri S, Mirahmadi A, Parvandi A, Hosseini-Monfared P, Minaei Noshahr R, Hoseini SM, Kazemi SM. Management of Iatrogenic Medial Collateral Ligament Injury in Primary Total Knee Arthroplasty: A Systematic Review. Arch Bone Jt Surg. 2024; 12(3): 159-166. doi: 10.22038/ABJS.2023.73563.3406. PMID: 38577515; PMCID: PMC10989723.
41.   Baldini A, Castellani L, Traverso F, Balatri A, Balato G, Franceschini V. The difficult primary total knee arthroplasty: a review. Bone Joint J. 2015 Oct; 97-B(10 Suppl A): 30-9. doi: 10.1302/0301-620X.97B10.36920. PMID: 26430084.
42.   Shahcheraghi GH, Javid M, Tavakoli A, Nirooei E, Momtahan E. Knee Arthroplasty without Metal Augmentations in Patients with Major Tibial Defects: A Retrospective Study. Iran J Med Sci. 2024 Nov 1; 49(11): 707-715. doi: 10.30476/ijms.2024.100363.3265. PMID: 39678526; PMCID: PMC11645414.
43.   Tani I, Nakano N, Takayama K, Ishida K, Kuroda R, Matsumoto T. NAVIGATED TOTAL KNEE ARTHROPLASTY FOR OSTEOARTHRITIS WITH EXTRA-ARTICULAR DEFORMITY. Acta Ortop Bras. 2018 May-Jun; 26(3): 170-174. doi: 10.1590/1413-785220182603178367. PMID: 30038540; PMCID: PMC6053962.
44.   Haritinian EG, Pimpalnerkar AL. Computer Assisted Total Knee Arthroplasty: Does it Make a Difference? Maedica (Bucur). 2013 Jun; 8(2): 176-81. PMID: 24371482; PMCID: PMC3865127.
45.   Matassi F, Cozzi Lepri A, Innocenti M, Zanna L, Civinini R, Innocenti M. Total Knee Arthroplasty in Patients With Extra-Articular Deformity: Restoration of Mechanical Alignment Using Accelerometer-Based Navigation System. J Arthroplasty. 2019 Apr; 34(4): 676-681. doi: 10.1016/j.arth.2018.12.042. Epub 2019 Jan 5. PMID: 30685259.
46.   Pietsch M, Hochegger M, Djahani O, Mlaker G, Eder-Halbedl M, Hofstädter T. Handheld computer-navigated constrained total knee arthroplasty for complex extra-articular deformities. Arch Orthop Trauma Surg. 2021 Dec; 141(12): 2245-2254. doi: 10.1007/s00402-021-04053-1. Epub 2021 Jul 13. PMID: 34255171.
47.   Rhee SJ, Seo CH, Suh JT. Navigation-assisted total knee arthroplasty for patients with extra-articular deformity. Knee Surg Relat Res. 2013 Dec; 25(4): 194-201. doi: 10.5792/ksrr.2013.25.4.194. Epub 2013 Nov 29. PMID: 24368997; PMCID: PMC3867612.
48.   Alturki AA, Alshammari NA, Albassam AL, Aljaafri ZA, Almugren TS. Robotic-assisted total knee arthroplasty for extra-articular femur deformity correction. J Surg Case Rep. 2023 Jul 8; 2023(7): rjad395. doi: 10.1093/jscr/rjad395. PMID: 37434720; PMCID: PMC10331803.
49.   Cook-Richardson, Sharma, Desai, Rasesh, Robotic Arm-Assisted Total Knee Arthroplasty in the Setting of Combined Extra-articular Deformities of the Femur and Tibia, Case Reports in Orthopedics, 2020, 5489646, 6 pages, 2020. https://doi.org/10.1155/2020/5489646
50.   Sodhi N, Khlopas A, Ehiorobo JO, Condrey C, Marchand K, Marchand RC, Hepinstall MS, Mont MA. Robotic-Assisted Total Knee Arthroplasty in the Presence of Extra-Articular Deformity. Surg Technol Int. 2019 May 15; 34: 497-502. PMID: 30888672.
51.   Wang JW, Wang CJ. Total knee arthroplasty for arthritis of the knee with extra-articular deformity. J Bone Joint Surg Am. 2002 Oct; 84(10): 1769-74. doi: 10.2106/00004623-200210000-00005. PMID: 12377906.
52.   Catonné Y, Sariali E, Khiami F, Rouvillain JL, Wajsfisz A, Pascal-Moussellard H. Same-stage total knee arthroplasty and osteotomy for osteoarthritis with extra-articular deformity. Part I: Tibial osteotomy, prospective study of 26 cases. Orthop Traumatol Surg Res. 2019 Oct; 105(6): 1047-1054. doi: 10.1016/j.otsr.2019.04.010. Epub 2019 Jun 14. PMID: 31208931.
53.   Paredes-Carnero X, Escobar J, Galdo JM, Babé JG. Total knee arthroplasty for treatment of osteoarthritis associated with extra-articular deformity. J Clin Orthop Trauma. 2018 Apr-Jun; 9(2): 125-132. doi: 10.1016/j.jcot.2017.01.004. Epub 2017 Jan 22. PMID: 29896014; PMCID: PMC5995007.
54.   Sobhi S, Khan RJK, Fick DP, Finsterwald M. Prevalence of extra-articular tibia valga morphology in valgus knees and its implications for primary total knee arthroplasty. J Orthop Surg Res. 2022 Dec 9; 17(1): 531. doi: 10.1186/s13018-022-03418-5. PMID: 36494825; PMCID: PMC9733362.
55.   Arbeloa-Gutierrez L, Arenas-Miquelez A, de Pablos J. Knee osteoarthritis associated with extra-articular deformity treated by total knee arthroplasty plus simultaneous corrective osteotomy. Rev Esp Cir Ortop Traumatol. 2024 Sep 25: S1888-4415(24)00152-8. English, Spanish. doi: 10.1016/j.recot.2024.09.006. Epub ahead of print. PMID: 39332756.
56.   de Pablos Fernández J, Arbeloa-Gutierrez L, Arenas-Miquelez A. One-Stage Total Knee Arthroplasty Plus Corrective Osteotomy for Osteoarthritis Associated With Severe Extra-articular Deformity. Arthrosc Tech. 2019 Nov 13; 8(11): e1403-e1410. doi: 10.1016/j.eats.2019.07.020. PMID: 31890514; PMCID: PMC6926380.
57.   Hosseini-Monfared P, Mirahmadi A, Amiri S, Minaie R, Ghafouri MH, Kazemi SM. Comparable long-term functional outcomes of subvastus and medial parapatellar approach in total knee arthroplasty: A 10-year follow-up study. J Exp Orthop. 2024 Oct 8; 11(4): e70035. doi: 10.1002/jeo2.70035. PMID: 39380847; PMCID: PMC11460747.
58.   Demir B, Özkul B, Saygılı MS, Çetinkaya E, Akbulut D. Deformity correction with total knee arthroplasty for severe knee osteoarthritis accompanying extra-articular femoral deformity: the results are promising. Knee Surg Sports Traumatol Arthrosc. 2018 Nov; 26(11): 3444-3451. doi: 10.1007/s00167-018-4920-8. Epub 2018 Apr 9. PMID: 29632977.
59.   Xiao-Gang Z, Shahzad K, Li C. One-stage total knee arthroplasty for patients with osteoarthritis of the knee and extra-articular deformity. Int Orthop. 2012 Dec; 36(12): 2457-63. doi: 10.1007/s00264-012-1695-2. Epub 2012 Nov 7. PMID: 23132502; PMCID: PMC3508045.
60.   Cozzi Lepri A, Innocenti M, Matassi F, Villano M, Civinini R, Innocenti M. Accelerometer-Based Navigation in Total Knee Arthroplasty for the Management of Extra-Articular Deformity and Retained Femoral Hardware: Analysis of Component Alignment. Joints. 2019 Oct 11; 7(1): 1-7. doi: 10.1055/s-0039-1697610. PMID: 31879723; PMCID: PMC6930126.
61.   Klein GR, Austin MS, Smith EB, Hozack WJ. Total knee arthroplasty using computer-assisted navigation in patients with deformities of the femur and tibia. J Arthroplasty. 2006 Feb; 21(2): 284-8. doi: 10.1016/j.arth.2005.07.013. PMID: 16520220.
62.   Thienpont E, Paternostre F, Pietsch M, Hafez M, Howell S. Total knee arthroplasty with patient-specific instruments improves function and restores limb alignment in patients with extra-articular deformity. Knee. 2013 Dec; 20(6): 407-11. doi: 10.1016/j.knee.2013.07.001. Epub 2013 Jul 27. PMID: 23899651.
63.   Mirahmadi A, Hosseini-Monfared P, Amiri S, Taheri F, Farokhi M, Minaei Noshahr R, Kazemi SM. Cross‑cultural adaptation and validation of the Persian version of the new Knee Society Knee Scoring System (KSS). J Orthop Surg Res. 2023 Nov 13; 18(1): 858. doi: 10.1186/s13018-023-04347-7. PMID: 37953297; PMCID: PMC10641991.
64.   Collins NJ, Misra D, Felson DT, Crossley KM, Roos EM. Measures of knee function: International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form, Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS), Knee Outcome Survey Activities of Daily Living Scale (KOS-ADL), Lysholm Knee Scoring Scale, Oxford Knee Score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Activity Rating Scale (ARS), and Tegner Activity Score (TAS). Arthritis Care Res (Hoboken). 2011 Nov; 63 Suppl 11(0 11): S208-28. doi: 10.1002/acr.20632. PMID: 22588746; PMCID: PMC4336550.
65.   Huang TW, Chuang PY, Lee CY, Lin SJ, Huang KC, Shen SH, Tsai YH, Lee MS, Hsu RW. Total knee arthroplasty in patients with Ranawat type-II valgus arthritic knee with a marked coronal femoral bowing deformity: comparison between computer-assisted surgery and intra-articular resection. J Orthop Surg Res. 2016 Aug 3; 11(1): 88. doi: 10.1186/s13018-016-0422-x. PMID: 27488841; PMCID: PMC4973030.
66.   Sun JY, Zhang GQ, Shen JM, Du YQ, Li TJ, Geng ZJ, Zhou YG, Wang Y. Single-stage total knee arthroplasty and femoral osteotomy for osteoarthritis with severe supracondylar deformity. J Orthop Surg Res. 2021 Feb 20; 16(1): 149. doi: 10.1186/s13018-021-02293-w. PMID: 33610184; PMCID: PMC7896386.
67.   Fukushima A, Iwasaki K, Hishimura R, Matsubara S, Joutoku Z, Matsuoka M, Endo T, Onodera T, Kondo E, Iwasaki N. Three-stage total knee arthroplasty combined with deformity correction and leg lengthening using Taylor spatial frames and conversion to internal fixation for severe intra- and extra-articular deformities and hypoplasia in a patient with hemophilic knee arthropathy: A case report. Knee. 2023 Jan; 40: 90-96. doi: 10.1016/j.knee.2022.10.009. Epub 2022 Nov 18. PMID: 36410255.
68.   Baek JH, Lee SC, Ryu S, Ahn HS, Nam CH. Coronal Correction for Post-Traumatic Malalignment Using Robot-Assisted Total Knee Arthroplasty: A Case Series. Orthop Res Rev. 2022 Nov 22; 14: 445-451. doi: 10.2147/ORR.S387957. PMID: 36444241; PMCID: PMC9700467.
69.   Moyad TF, Estok D. Simultaneous femoral and tibial osteotomies during total knee arthroplasty for severe extra-articular deformity. J Knee Surg. 2009 Jan; 22(1): 21-6. doi: 10.1055/s-0030-1247722. PMID: 19216348.
70.   Lin SY, Chen CH, Huang PJ, Fu YC, Huang HT. Computer-navigated minimally invasive total knee arthroplasty for patients with retained implants in the femur. Kaohsiung J Med Sci. 2014 Aug; 30(8): 415-21. doi: 10.1016/j.kjms.2014.03.007. Epub 2014 May 6. PMID: 25002380; PMCID: PMC11916698.
71.   Matheen FIA, Leong JF, Abdul Rani R, Hayyun MF, Mohamad Yahaya NH. Malunion of a Floating Knee: Overcoming the Challenges of Extra-articular Deformities With a Robotic-Arm-Assisted Total Knee Arthroplasty. Cureus. 2024 Sep 2; 16(9): e68482. doi: 10.7759/cureus.68482. PMID: 39364451; PMCID: PMC11446639.
 
.