نوع مقاله : مروری
نویسندگان
1 گروه بیهوشی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران
2 گروه بیهوشی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران.
3 گروه ارتوپدی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران.
کلیدواژهها
موضوعات
عنوان مقاله English
نویسندگان English
Intrathecal opioids, such as morphine and fentanyl, are increasingly being used as adjuncts to spinal anesthesia and improve the quality of pain relief during and after surgery. This review investigates the mechanisms, benefits, and side effects of using these opioids, particularly in the context of femoral surgeries. The pharmacokinetics of these agents, including their rapid distribution in cerebrospinal fluid and binding to spinal receptors, contribute to effective pain management but also carry risks such as respiratory depression and urinary retention. Additionally, the impact of hemodynamic changes in femoral surgery is reviewed, emphasizing the importance of carefully adjusting anesthetic regimens and close postoperative monitoring to minimize complications. Evidence suggests that intrathecal opioids may reduce the incidence of postoperative delirium and opioid consumption in elderly patients, although further research is needed to confirm their efficacy in various surgical settings. This review underscores the need for more research into multimodal pain control using intrathecal opioids.
کلیدواژهها English
