The Effect of Nanotubes on the Shape Memory Alloy Surface and Biological Properties of Nickel-Titanium (Nitinol) in Orthopaedic Implants (A review paper)

Jafargholizadeh, Banafsheh; Hassanzadeh Nemati, Nahid

doi:10.22034/ijos.2022.318568.1015

The Effect of Nanotubes on the Shape Memory Alloy Surface and Biological Properties of Nickel-Titanium (Nitinol) in Orthopaedic Implants (A review paper)

Document Type : Review

Authors

Banafsheh Jafargholizadeh ¹

Nahid Hassanzadeh Nemati ²

¹ PhD Candidate, Department of Medical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

² Assistant Professor, Department of Medical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

https://doi.org/10.22034/ijos.2022.318568.1015

Abstract

Introduction: An increasing population of the elderly has led to increasing demand for orthopedic implants. Excellent biocompatibility of orthodontic wires, drug delivery systems, cardiovascular stents, and orthopedic implants has attracted widespread attention by researchers for use in medical industries. In some cases, however, superficial properties such as corrosion resistance and other biological behavior are not sufficient for clinical application. Infection caused by the presence of implants in the body is one of the most common complaints of patients. Since the bacteria play important role in patients ’disability, the development of antibacterial properties has been considered.
Methods: Nanotubes, created on the surface of nitinol through anodizing, can be one of the useful solutions in creating antibacterial properties. Also, the ability of these structures to carry drugs such as antibiotics can solve the problems caused by implantation of orthopedic implants in the body.
Results: In order to increase the long-term antibacterial ability of orthopedic implants, the researchers have improved the physical properties by modification of nitinol levels by anodizing method and the formation of nanotubes on its surface and drug loading.
Conclusion: The effect of different parameters on morphology, nickel ion release, corrosion behavior, biological and drug delivery, applicable in orthopedic implants, is discussed.

Keywords

Shape memory alloys

Nitinol

prosthesis implantation

Nanotubes

drug delivery