Author
Abstract
Aseptic loosening in total hip arthroplasty (THA) is among the common reasons for failure and the need for revision surgery. There is no general consensus among the orthopaedic surgeons as to the true reason for this pathology. Some consider this a purely mechanical failure, related to the long-standing forces applied to the joint, causing fatigue failure, while others consider it purely biological response of the body to the particulate debris resulting from the wear in polyethylene or other components of the THA causing linear osteolysis. A combined pathology is probably a more logical explanation, i.e. osteolysis weakening the prosthetic bone in-growth, making it more susceptible to shear, and rotational forces and eventually causing the loosening. Here in, an overview of pathophysiology, prevention, diagnosis and treatment of hip aseptic loosening has been presented.
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