Basic
Vahid Zarghami; Fereshteh Moharramzadeh Jeghanab; Mohammad Ali Shokrgozar
Abstract
Background: One of the issues related to stimulating and accelerating bone regeneration and bone repair is the role of the immune system in fracture healing, known as osteo-immunology.Method: In these review 57 articles of science direct and pumped database is investigated for potential role and mechanism ...
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Background: One of the issues related to stimulating and accelerating bone regeneration and bone repair is the role of the immune system in fracture healing, known as osteo-immunology.Method: In these review 57 articles of science direct and pumped database is investigated for potential role and mechanism of the immune system's response to bone fracture. Results: biological materials such as tumor necrosis factor alpha (TNF-α), lipopolysaccharide (LPS), interleukin-17 (IL-17) protein, lipotic Acid (LTA) could regulate the immune system, which have the ability to improve the ossification process and faster healing.Conclusion: The direction of future research was predicted regarding the emergence of new therapeutic compounds derived from bone-building materials such as bone growth factors and substances that regulate the behaviour of the immune system in order to regenerate bone.
