Scaffolds Applied in Tissue Engineering: A Review on Previous Gains and Challenges(Review Article)

Shams, Mohammadhossein; Atabakhsh, Azin; Safari, Mohammadreza

doi:10.22034/ijos.2025.475958.1105

Scaffolds Applied in Tissue Engineering: A Review on Previous Gains and Challenges(Review Article)

Document Type : Review

Authors

Mohammadhossein Shams ¹

Azin Atabakhsh ¹

Mohammadreza Safari ²

¹ Student research committee, Hamedan university of medical sciences and health services, Hamedan, Iran

² Department of medical laboratory, school of paramedicine, hamedan university of medical sciences and health services, Hamedan, Iran

https://doi.org/10.22034/ijos.2025.475958.1105

Abstract

Abstract

Tissue engineering is a modern and interdisciplinary science that examines the methods used in the structural and functional restoration of damaged tissues. One of the most important steps in tissue engineering is to prepare a suitable scaffold with characteristics compatible with the target tissue. In recent years, many scaffolds have been prepared, to repair different tissues. The present study examines recent research in the preparation of scaffolds in various tissue engineering. Many scaffolds including composites, nanofibers, hydrogels, synthetic or semi-synthetic polymers and ceramics have been prepared and used. Some scaffolds are also obtained during decellularization of natural tissues. Various methods, like electrospinning or 3D printing, have been used to prepare synthetic scaffolds. However, there is a need for more in-vivo studies to ensure the proper functioning of these scaffolds in in-body conditions.

Keywords

Tissue engineering, Regenerative medicine, Tissue scaffolds, Composite tissue allograft

Subjects