Methods: In a case series study, cases of osteonecrosis in Akhtar hospital in Tehran with history of temgesic and norgesic abuse were identified in a 2 year period. The hospital charts of 11 cases with such characteristics were evaluated.Results: Eleven cases with mean age of 37.72±5.55 years comprised the study group. Five cases had used norgesic, 5 temgesic and 1 patient had used both of those agents. The average drug dosage was 4.36±2.29 vials per day for an average of 4.9±2.9 months. Onset of symptoms was 11.36±2.76 months after drug usage on average. Three cases had skin stria and 7 patients had localized obesity, both suggesting steroid effect. Bilateral involvement of bone ends was observed in all, while 3 cases had more than two joints affected.Conclusions: Norgesic and temgesic cause osteonecrosis with severe joint destruction. Raising the awareness of general public and physicians towards such a devastating complication is warranted.
Kazemi, MD,S M , Hosseinzadeh, MD,H , Aalami Harandi, MD,A and Ranjpour, MD,F R M . (2020). Osteonecrosis Following Temgesic/ Norgesic Addiction. Iranian Journal of Orthopedic Surgery, 5(3), 152-155. doi: 10.22034/ijos.2020.121218
MLA
Kazemi, MD,S M , , Hosseinzadeh, MD,H , , Aalami Harandi, MD,A , and Ranjpour, MD,F R M . "Osteonecrosis Following Temgesic/ Norgesic Addiction", Iranian Journal of Orthopedic Surgery, 5, 3, 2020, 152-155. doi: 10.22034/ijos.2020.121218
HARVARD
Kazemi, MD S M, Hosseinzadeh, MD H, Aalami Harandi, MD A, Ranjpour, MD F R M. (2020). 'Osteonecrosis Following Temgesic/ Norgesic Addiction', Iranian Journal of Orthopedic Surgery, 5(3), pp. 152-155. doi: 10.22034/ijos.2020.121218
CHICAGO
S M Kazemi, MD, H Hosseinzadeh, MD, A Aalami Harandi, MD and F R M Ranjpour, MD, "Osteonecrosis Following Temgesic/ Norgesic Addiction," Iranian Journal of Orthopedic Surgery, 5 3 (2020): 152-155, doi: 10.22034/ijos.2020.121218
VANCOUVER
Kazemi, MD S M, Hosseinzadeh, MD H, Aalami Harandi, MD A, Ranjpour, MD F R M. Osteonecrosis Following Temgesic/ Norgesic Addiction. Iranian Journal of Orthopedic Surgery. 2020;5(3):152-155 (In Persian). doi: 10.22034/ijos.2020.121218
