Methods: In a case series study, cases of osteonecrosis in Akhtar hospital in Tehran with history of temgesic and norgesic abuse were identified in a 2 year period. The hospital charts of 11 cases with such characteristics were evaluated.Results: Eleven cases with mean age of 37.72±5.55 years comprised the study group. Five cases had used norgesic, 5 temgesic and 1 patient had used both of those agents. The average drug dosage was 4.36±2.29 vials per day for an average of 4.9±2.9 months. Onset of symptoms was 11.36±2.76 months after drug usage on average. Three cases had skin stria and 7 patients had localized obesity, both suggesting steroid effect. Bilateral involvement of bone ends was observed in all, while 3 cases had more than two joints affected.Conclusions: Norgesic and temgesic cause osteonecrosis with severe joint destruction. Raising the awareness of general public and physicians towards such a devastating complication is warranted.
Kazemi, MD, S. M., Hosseinzadeh, MD, H., Aalami Harandi, MD, A. & Ranjpour, MD, F. R. M. (2020). Osteonecrosis Following Temgesic/ Norgesic Addiction. Iranian Journal of Orthopedic Surgery, 5(3), 152–155. https://doi.org/10.22034/ijos.2020.121218
MLA
Kazemi, MD, S. M., Hosseinzadeh, MD, H., Aalami Harandi, MD, A., & Ranjpour, MD, F. R. M. "Osteonecrosis Following Temgesic/ Norgesic Addiction", Iranian Journal of Orthopedic Surgery, 5, 3, 2020, 152–155. doi: 10.22034/ijos.2020.121218
HARVARD
Kazemi, MD, S. M., Hosseinzadeh, MD, H., Aalami Harandi, MD, A., & Ranjpour, MD, F. R. M. (2020). 'Osteonecrosis Following Temgesic/ Norgesic Addiction', Iranian Journal of Orthopedic Surgery, 5(3), pp. 152–155. doi: 10.22034/ijos.2020.121218
CHICAGO
Kazemi, MD, S. M., Hosseinzadeh, MD, H., Aalami Harandi, MD, A. & Ranjpour, MD, F. R. M., "Osteonecrosis Following Temgesic/ Norgesic Addiction." Iranian Journal of Orthopedic Surgery, 5 3 (2020): 152–155, doi: 10.22034/ijos.2020.121218
VANCOUVER
Kazemi, MD S. M., Hosseinzadeh, MD H., Aalami Harandi, MD A., Ranjpour, MD F. R. M. Osteonecrosis Following Temgesic/ Norgesic Addiction. Iranian Journal of Orthopedic Surgery. 2020;5(3):152–155 (In Persian). doi: 10.22034/ijos.2020.121218
