Treatment of Femoral Head Osteonecrosis by Core Decompression with and without Autograft of Concentrated Mononuclear Cells Infusion (A Comparative Study)
Volume 10, Issue 2, Spring 2012, Pages 53-58
https://doi.org/10.22034/ijos.2020.121060
Sadegh Saberi, Mahmood Farzan, Reza Mostafavi Tabatabaee
Abstract Background: The use of stem cell is believed to reduce pain and delay the deterioration in the early stages of femoral head osteonecrosis.The aim of this study was to evaluate the effect of autologus concentrated mononuclear bone marrow cell implantation after core decompression in femoral heads that were in the early stages of osteonecrosis. Methods: Twenty eight femoral heads with osteonecrosis that were undergoing core decompression were randomly divided into two groups of 14. One group received additional implantation of autologus bone marrow mononuclear cells. The two groups were, then evaluated within 2 years with WOMAC (Western Ontario and McMaster University osteoarthritis index), visual analogue pain index (VAS) and MRI of the femoral heads. Results: A significant improvement in WOMAC, and VAS scores was observed within the 2 years of follow-up in the implanted group, compared to the control group (p < /i>=.046), with 3 cases showing change to a lower osteonecrosis stage. The control group, on the other hand, showed worsening in the osteonecrotic heads (p < /i>
Patient Satisfaction after Spinal Decompression in Central Degenerative Spinal Stenosis (An early result)
Volume 4, Issue 4, Summer 2006, Pages 8-13
https://doi.org/10.22034/ijos.2020.121238
Bahram Mobini, MD, Hamid Behtash, MD, Ebrahim Ameri, MD, Seyed Alireza Bassampoor, MD
Abstract Background: Spinal stenosis is a common reason for referral to a spine center by adults. Pain and numbness in buttochs and lower limbs after a period of standing or walking are the common complaints. History, supplemented with good physical exam radiography and MRI of spine are the mainstays of diagnosis. Spinal decompression is the final step in treatment, which is not always associated with long term patients’ satisfaction.Methods: 38 patients with mean age of 56 years who had undergone posterior spinal decompression were retrospectively studied. The pre and post operative activity level and their degree of satisfaction were assessed.Results: In a 2-4 year follow-up period, 30 patients were satisfied with their operations, and no surgical complication had been experienced. In 30 patients (79%) back pain had aggravated. 3 folds improvement in standing or walking was reported by 29 cases, and 21 patients (57%) returned to their previous activity level. Conclusions: In short time, spinal decompression can effectively relieve the symptoms, but can not reduce back pain symptoms. Despite higher age range for this surgery, early complication rate is very low.