Iranian Journal of Orthopedic Surgery

Abstract Background: Rupture of tendons is a common injury. The outcome of surgical repair of injured tendon is often unsatisfactory.  At best, the restored tendon is about half of its initial mechanical properties. In this study the effect of zenologous and autologous platelet gel were compared in rabbit model. Methods: 45 rabbits in the age range of 7 months to 1 year old were divided into autologous, zenologous and control groups. Superficial digital flexor tendon was cut transversely and then sutured with Mayer stitch pattern. Then 5cc of either aotologous or zenologous platelet gel was injected to the incision area. The control group had no material injection. On 7th, 14th, and 28th post-operative days, five rabbits of each group were euthanized and tendons were harvested for histopathological and biomechanical evaluations. The results were analyzed statistically. Results: Biomechanical factors were significantly superior in the autologous and zenologous groups than the control group. In histopathological examination the autologous groups showed a significant difference in fibroblast maturation in all the tested weeks. The collagen fiber alignment at 7th postoperative day and collagen accumulation on 7th and 28th postoperative days were superior in autologous compared with zenologous and control groups. Conclusions: Utilization of zenologous platelet gel has a positive effect on tendon healing, but not as good as autologous platelet gel.

Abstract Background: Hand injury is the most frequent body injury, requiring long duration of treatment with great cost to any community. The aim of this study is to review the epidemiology of such an organ in a teaching unit in Tehran, Iran.Methods: Between a period of one year, 2042 patients were treated for hand injuries in a referral center for hand injuries in Tehran. Age, sex, cause and place of injury, mechanism and type of trauma, traumatized structures, duration of admission, type of treatment and type of insurance were evaluated.Results: 2042 patients (89.3% male, 10.7% female) referred to this hospital with hand injury. The average age was 26.8±11.9 years. The predominant group was industrial workers (65.6%). Men were mostly injured by mechanical instruments and women by glass cuts. Children were more commonly injured by door closing on their fingers or cut by glass. Bony fractures were seen in 34.7% of the cases. Tendon and nerve were the most common structures injured. The majority of injuries were sharp lacerations. The mean hospital stay was 1.33 days (1-49 days). 58.36% of the cases have insurance coverage admission.Conclusion: hand injuries are seen more commonly in men, in particular industrial workers. Tendon and nerve injuries are most common afflicted and one third of cases have bony injuries.