Iranian Journal of Orthopedic Surgery

Abstract Abstract
Introduction: In some cases of major lower limb trauma, either amputation or limb preservation is performed. The aim of this study was to compare the quality of life in patients undergoing amputation versus limb preservation.
Materials & Methods: In a cross-sectional comparative study, patients with major lower limb trauma who underwent either lower limb amputation or limb preservation were evaluated at least six months post injury. Quality of life was assessed and compared between the two groups using SF-36 questionnaire.
Results & Discussion: A total of 94 patients, including 80.9% male and 0.9% female, with mean age of 41.5 years (range 18 to 64), with the mean study period of 6 months, were included in the study. There was no statistically significant difference between the two study groups regarding age, gender, marital status, number of children, education level, smoking, or substance and alcohol abuse. The sub-scales of general health (P = 0.001) and vitality (energy) (P = 0.002) were significantly higher in the amputation group in comparison with the limb-preservation group within the six- months post injury.
Conclusion: In patients with major trauma, attempts to preserve the limb, instead of immediate amputation results into longer hospital stays, increased incidence of infections, and higher rates of re-operation. Amputation, within a minimum of six months, leads to improved quality of life, particularly in the domains of general health and vitality.

Abstract Abstract
Background: Osteoporosis is the most common bone metabolic disease. The purpose of this study was to evaluate the effect of anti-osteoporosis treatment with bisphosphonate and parathyroid on bone repair in patients with osteoporosis related fractures.
Methods: This single-blind randomized controlled clinical trial was performed on three groups of 20 patients each (parathyroid hormone, alendronate and control) with osteoporosis fractures hospitalized in orthopedic ward of Emam Khomeini and Boali Sinaye Sari hospitals during 2016-2018. All the patients were assessed at the 4th, 8th, and 12th week in terms of union.
Results: While no union was reported at the end of the fourth week, 20, 18, and 17 subjects respectively on CinnoPar, alendronate and control groups had union at the end of the eighth week. Furthermore, the complete union was achieved for all patients in the 12th week.
Conclusions: According to the results of the study, no significant difference was observed in the repair of osteoporotic fractures of distal radius by alendronate and parathyroid hormone.